D9628

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D9628

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3,4-Dihydroxy-L-phenylalanine

Synonym:3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-DOPA, Levodopa
CAS Number:59-92-7
Linear Formula:(HO)2C6H3CH2CH(NH2)CO2H
Molecular Weight:197.19
Beilstein Registry Number:2215169
EC Number:200-445-2
MDL number:MFCD00002598
PubChem Substance ID:24277914

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Description

Biochem/physiol ActionsNatural isomer of the immediate precursor of dopamine; product of tyrosine hydroxylase

Properties

mp276-278 °C(lit.)

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXn
Risk Statements22-36/37/38
Safety Statements26-36
WGK Germany3
RTECSAY5600000

References

referenceDe Souza Silva, et al., Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat. J. Neurochem. 68, 233-239, (1997) Abstract
 Tabar, et al., The effects on central dopamine function of chronic L-DOPA (methyl ester hydrochloride) treatment of mice. Pharmacol. Biochem. Behav. 33, 139, (1989) Abstract
 Feigin, A., Metabolic correlates of levodopa response in Parkinson's disease. Neurology 57, 2083, (2001)
MerckMerck 13,5485
BeilsteinBeil. 14,IV,2492
 FT-IR 2 (2), 2753:A / FT-IR 1 (2), 257:B / FT-NMR 1 (2), 1190:B / IR-Spectra (3), 999:A / IR-Spectra (2), 874:F / RegBook 1 (2), 1847:I / Sax 6, 1076 / Sigma FT-IR 1 (1), 139:B / Structure Index 1, 296:A:5